[ PAPER ] · 1999 · New England Journal of Medicine
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.
Paul C. Hébert, G. Wells, M. Blajchman, John C. Marshall, C. Martin, G. Pagliarello, M. Tweeddale, I. Schweitzer, E. Yetisir
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[ TLDR ]
A restrictive strategy of red-cell transfusion is at least as effective as and possibly superior to a liberal transfusion strategy in critically ill patients, with the possible exception of patients with acute myocardial infarction and unstable angina.